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Devi, P.
- Studies on Antimicrobial and Anti-Inflammatory Activity of the Siddha Formulation (Thailam - Medicated Oil)
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Authors
Affiliations
1 Shri Sarvajanik Pharmacy College, Near Arvind Baug, Mehsana-384001, North Gujarat, IN
2 K.M. College of Pharmacy, Uthangudi, Melur Road, Madurai, Tamilnadu-625107, IN
1 Shri Sarvajanik Pharmacy College, Near Arvind Baug, Mehsana-384001, North Gujarat, IN
2 K.M. College of Pharmacy, Uthangudi, Melur Road, Madurai, Tamilnadu-625107, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 1 (2010), Pagination: 83-88Abstract
Pongamia pinnata and Boerhaavia diffusa are well-known plants and a weed respectively plays in Indian traditional system of medicine. On the basis of its traditional use and literature references, these herbal plants are undertaken in a view to formulate milder and safer herbal topical formulations. It is prepared in the form of "Thailam" using sesame oil as base for bringing about the anti-inflammatory and antimicrobial drugs. To satisfy the desired characteristic of an ideal herbal formulation and also to prove its therapeutic potency, the following parameters like physical, chemical and biological evaluation have undertaken to fix the quality. For the antimicrobial studies strains used like S. aureus, B. substilis (Gram +ve), E. coli, P. aeruginosa (Gram-ve) and Candida albicans, Aspergillus niger (Fungi) were used. Antibacterial activity and antifungal activity of the formulated oil was comparatively lesser than that of the standard drug but formulated oil is significantly more than that of sesame oil base (**P<0.01). By using Carrageenin induced hind paw edema method the Anti inflammatory activity was employed and it was noticed that the Thailam had lesser activity than the standard Diclofenac sodium gel (**P<0.01). But significantly more than that of sesame oil base (*P < 0.05), the overall results revealed that it has effectiveness. In conclusion that the formulated oil in the form of Thailam as its own significant properties, hence it can be used as a safer formulation in near future.Keywords
Formulated Oil (Thailam), Sesame Oil (Base), Carrageenin, Antimicrobial Strains.
References
- Chelladurai V. Medicinal plants of India, 2000, (2) 80:pp437, 493.
- Kiritikar, K.R. and Basu,B.D, Indian Medicinal Plants, 1987, I:pp830-832, III:pp1857-1861, IV:pp2044-2048.
- The wealth of India, publications and Information Directorate (CSIR), New Delhi 1972, II: pp174-176, VIII: pp204-210, IX:pp 278-281.
- Flora of the Gamble J.S., Presidency of Madras, Published under the authority of the Secretary of State for India in Council, 1935, I, II, III.
- Indian Pharmacopoeia, Pub. Govt. of India of Ministry of Health 1996, II, A-50, A-51, A-52, A-53, A-54, A-124, A-74.
- World Health Organization, Geneva, Quality Control methods for Medicinal plant materials, 1998:pp28, 30.
- Kokate.C.R., Practical Pharmacognosy, Pub, valiabh Prakasham, Delhi, 4th Edition 1994:pp108, 178-181.
- Badmanaban. R, Patel C.N and Devi. P, Physio-chemical investigation and wound healing activity of Sesame oil and formulated oil, Asian J. Research Chem. 2009; 2(4):501-505.
- Trease and Evan's, 14th Edition, 1997:pp179, 185, 180.
- British Pharmacopoeia, 1993, I: pp594.
- Indian Pharmacopoeia, pub. Govt. of India of Ministry of Health, 1966:pp640, 649-650.
- Remington - The science and practice of Pharmacy, 14th edition, 1920, I; pp965-970.
- Leo Lakhman, Herbert.A. Liberman, Kanig.T. The Theory and Practical of Industrial Pharmacy, 3rd Edition, 1987:pp314, 296-302, 487, 190-193.
- Satoshkar.R.S. Bhandarkar,S.D., Ainapure.S.S., 2001, 17th Edition, 154:pp835.
- Winter C.A, Rishley A.Nuss Gow, Soci. Exp. Biology, 1962, 3: 544.
- Singh H and Gosh M.N., J. Pharm, Pharmacology, 1968, 20:316.
- Kelley.W.B and Weiner, Text book of Rheumetology, Sanders Company, Philodelphia, 1981:pp1018.
- Armitage P, In. Statistical method in Medical Research, Blackwell Scientific publication, 1971: pp 217.
- Rathee.P.S., Mishra.S.H. and Kaushal.R., Indian Drugs, 1979, 16(9):207.
- Rathee. P.S., Mishra.S.H. and Kaushal.K., Indian Drugs, 1980, 17(5):136.
- Banerjee.A., and Nigam.S.S., Indian Drugs, 1980, 17(7):212.
- Evaluation of Anti-Inflammatory, Antipyretic and Antifungal Activity of Solanum laeve Dunal
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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, K. M. College of Pharmacy, Uthangudi, Madurai-625107, IN
2 K.M. College of Pharmacy, Uthangudi, Madurai– 625 107, IN
3 Department of Biotechnology, St. Michael College of Engineering, Sivagangai, TamilNadu, IN
1 Department of Pharmaceutical Chemistry, K. M. College of Pharmacy, Uthangudi, Madurai-625107, IN
2 K.M. College of Pharmacy, Uthangudi, Madurai– 625 107, IN
3 Department of Biotechnology, St. Michael College of Engineering, Sivagangai, TamilNadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 1 (2010), Pagination: 25-29Abstract
Solanum leave Dunal var biegninatum is small shrub is used by the tribals as a medicinal plant. The objective of the present investigation was to study the anti inflammatory, antipyretic and anti fungal activity potential in experimental animal models. The isolated compounds obtained from the chromatography after the extraction completed were used for (SA-I, SA-II, SA-III) these studies. Anti inflammatory potential of isolated compounds (SA-I, SA-II, SA-III) was evaluated by Carrageenan induced paw edema method in rats. Also antipyretic activity was tested on animal models. The studies were conducted on wistar rats of either sex (160-180g). The change in edema volume of the rat hind paw was measured using plethysmometer. The SA-III of isolated compound of Solanum leave dunal inhibited the formation of edema to significant levels in rats treated with carrageenan. At a dose of 100mg/kg orally, the SA-III produced 40.90% inhibition in case of the carrageenan induced edema (p<0.01).
The isolated compounds of Solanum leave Dunal (SA-I, SA-II,SA-III) were also evaluated for antipyretic activity on animals as per Vogel's method. Solanum leave Dunal elicited a dose dependent inhibition of rectal temperature compared with control group. The isolated compound SA-II having maximum antipyretic activity which was compared with standard inhibition at 300mg/kg p.o.
The fungal activity of the isolated compounds (SA-I,SA-II,SA-III) were prepared at various concentration of 1%,2% and 3% solution respectively. In this the compound SA-II(C) having significant antifungal activity compared with other compound against Candida albicans.
The results indicated that the isolated compounds (SA-I,SA-II,SA-III) were active against all the experimentally induced laboratory models of inflammation, pyretic activities and also antifungal activity.
- HPTLC Analysis and Phytochemical Investigation of Leaves of Euphoria longan
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Authors
Affiliations
1 K.M. College of Pharmacy, Uthangudi, Madurai-625107, Tamilnadu, IN
1 K.M. College of Pharmacy, Uthangudi, Madurai-625107, Tamilnadu, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 1 (2010), Pagination: 31-35Abstract
This paper deals with the detailed evaluation of the crude drug by WHO recommended physico-chemical and determinations and authentic phytochemical procedures. The physico-chemical, morphological and histochemical parameters presented in this paper may be proposed as parameters to establish the authenticity of and can possibly help to differentiate the drug from its other species.The presence study demonstrates the presence of some phytochemicals in various extracts and glycosides, saponins , tannins confirmed by HPTLC instrument of Camag system.Keywords
Euphoria longan, HPTLC, Proximate Analysis, Physico-Chemical Investigations.- Synthesis and Biological Screening of Some Novel 4-Thiazolidinone Derivatives
Abstract Views :155 |
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Authors
Affiliations
1 K.M. College of Pharmacy, Uthangudi, Madurai-625107, Tamil Nadu, IN
1 K.M. College of Pharmacy, Uthangudi, Madurai-625107, Tamil Nadu, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 529-535Abstract
A new series of substituted 4-thiazolidionones were synthesized by cyclization of Schiff’s bases with thiooglycollic acid. The substituted schiff’s bases were synthesized starting from substituted benzoic acid with thionyl chloride in 3 steps. The structures of the synthesized compounds have been established on the basis of physical and spectral data and are screened for anticonvulsant, antibacterial and anti hyperglycemic activities; some of them exhibited significant activity.Keywords
Substituted 4-Thiazolidinonnes, Anticonvulsant, Anti Hyperglycemic, Anti Bacterial.- Antibacterial Activity of Crude Extracts and Semi Synthetic Hydrazone Derivatives of Rimelia reticulata
Abstract Views :175 |
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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, K. M. College of Pharmacy, Madurai-625107 Tamilnadu, IN
2 Department of Pharmacognosy, K. M. College of Pharmacy, Madurai-625107 Tamilnadu, IN
3 Department of Biochemistry, K. M. College of Pharmacy, Madurai-625107, Tamilnadu, IN
1 Department of Pharmaceutical Chemistry, K. M. College of Pharmacy, Madurai-625107 Tamilnadu, IN
2 Department of Pharmacognosy, K. M. College of Pharmacy, Madurai-625107 Tamilnadu, IN
3 Department of Biochemistry, K. M. College of Pharmacy, Madurai-625107, Tamilnadu, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 445-447Abstract
Anti microbial activity of Ether, Acetone Dichloromethane extract and Choloroform extracts and semi synthetic derivatives of Rimelia reticulata were tested against Gram (+) and Gram (-) bacteria strains using zone of inhibition by Agar disc diffusion method.. The bacteria used in test were Gram positive (Staphylococus aureus, Bacillus subtilis and Micrococcus luteus and Gram negative (Escherichia coli, Salmonella typhi and Pseudomonas aureginosa). Moderate antibacterial activity for Ether and Dichloromethane extract, and in Chloroform extract having more than 100% activity and Acetone extract having (90%) activity in Gram (+) organism. In Gram (-) all the extracts having moderate activity (80%). In Semi synthetic derivatives of Rimelia reticulata the Gram (+) and Gram (-) organisms are used. Among the four derivatives 2,4 di nitro hydrazine derivative has more than (100%) activity and 4 nitro phenyl hydrazine, phenyl hydrazine having moderate (80%) activity against Gram (+). In Gram (-) Hydrazine hydrate has shown more than (100% ) and Phenyl hydrazine, 4 nitro phenyl hydrazine having (90%) activity. The standard drug used in this activity is Lincomycin. Based on the current findings it can be concluded that the lichen Rimelia reticulata posses potent antibacterial activity.Keywords
Rimelia reticulata, Antibacterial Activity, Agar Disc Diffusion Method, Crude Extracts, Semi Synthetic Derivatives.- Apoptosis Significance and Molecular Mechanisms-A Review
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Authors
Affiliations
1 Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
2 K.M. College of Pharmacy, Uthangudi, Madurai-625107, Tamilnadu, IN
1 Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
2 K.M. College of Pharmacy, Uthangudi, Madurai-625107, Tamilnadu, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 369-375Abstract
Apoptosis, a form of programmed cell death, is a pivotal defense against the occurrence of cancer and is essential to metazoans in maintaining tissue homeostasis. Apoptosis exhibits a distinctive phenotype and involves elimination of potentially deleterious cells. Many diseases have been associated with aberrantly regulated apoptotic cell death, ultimately leading to inhibition of apoptosis and propagation of diseases such as cancer. This review highlights the significance of apoptosis, molecular mechanisms of apoptosis and various methods of causing cell death.Keywords
Apoptosis, Programmed Cell Death, Significance, Mechanisms, Caspases, Bcl-2 Family.- Physio-Chemical Investigation and Wound Healing Activity of Sesame Oil and Formulated Oil
Abstract Views :151 |
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Authors
Affiliations
1 Shri Sarvajanik Pharmacy College, Mehasana, North Gujarat, IN
2 K.M. College of Pharmacy, Uthangudi, Madurai, IN
3 St. Michael College of Engineering, Kalayarkovil, Tamilnadu, IN
1 Shri Sarvajanik Pharmacy College, Mehasana, North Gujarat, IN
2 K.M. College of Pharmacy, Uthangudi, Madurai, IN
3 St. Michael College of Engineering, Kalayarkovil, Tamilnadu, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 501-505Abstract
Formulated oil a Siddha formulation was developed using two plant drugs namely Pongamia pinnata seeds and Boerhaavia diffusa ischolar_mains. Preliminary physio chemical screening was performed in both the plants. The wound healing activity was studied with comparison of Sesame oil and Formulated oil by using standard nitro furazone ointment. The methods used were Excision wound model, Incision wound model and Dead space wound model. In excision and incision wound model the formulated oil treated group showed much greater increase in the tensile strength when compared to the control, which was almost similar to that of nitro furazone. In the dead space wound model both the sesame oil and formulated oil produced a significant increase in the wet granuloma tissue weight as well as in the dry weight .Tensile strength was also found to be increased (P<0.001) in both of the oil treated groups.Keywords
Pongamia pinnata, Boerhaavia diffusa, Sesame Oil, Formulated Oil, Wound Healing Activity.- Phyto-Physico Chemical Evaluation, Anti-Inflammatory and Anti Microbial Activities of Aerial Parts of Gmelina asiatica
Abstract Views :182 |
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Authors
Affiliations
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamilnadu, IN
2 Department of Pharmacognosy, K. M. College of Pharmacy, Uthangudi, Madurai-625107, Tamilnadu, IN
3 Department of Pharmaceutical Chemistry, K. M. College of Pharmacy, Uthangudi, Madurai-625107, Tamilnadu, IN
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamilnadu, IN
2 Department of Pharmacognosy, K. M. College of Pharmacy, Uthangudi, Madurai-625107, Tamilnadu, IN
3 Department of Pharmaceutical Chemistry, K. M. College of Pharmacy, Uthangudi, Madurai-625107, Tamilnadu, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 1 (2009), Pagination: 76-82Abstract
The present study was carried out to investigate the anti inflammatory, anti bacterial and anti fungal activity of of petroleum ether, chloroform, ethyl acetate and ethanolic extract obtained from Gmelina asiatica. All the extracts were prepared from aerial parts of Gmelina asiatica by hot percolation method in soxhlet apparatus. All extracts of Gmelina asiatica were tested for antibacterial efficacy against Bacillus subtilis, Staphylococcus aureus, Micrococcus luteus, Escherichia coli, Salmonella typhi and pseudomonas aeruginosa and antifungal efficacy against Candida albicans and Aspergillus niger. The Antibacterial and Anti fungal effect produced by petroleum ether, chloroform, ethyl acetate and ethanol extract were comparable to that of Amikacin and Griseofulvin. The Chloroform extract was found to be more effective and showed Anti bacterial and antifungal activity against the entire organism tested. All the extracts at dose concentration (500 mg/kg) were screened for antimicrobial activity. The ethanolic extract of Gmelina asiatica at (250 and 500 mg/kg) concentrations exhibited anti inflammatory activity in carrageenan induced rat paw oedema, histamine induced odema, dextran induced odema and cotton pellet induced granuloma method, and the results are compared to that of standard drug Indomethacin. The results were found to be significiant (P<0.001) when compared to control.Keywords
Gmelina asiatica, Anti-Inflammatory Activity, Indomethacin, Antimicrobial Activity, Amikacin, Anti Fungal Activity, Griseofulvin.- Privacy Preserving M2M-Iot Environment
Abstract Views :168 |
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Authors
Affiliations
1 Department of Computer Science and Engineering, Hindustan Institute of Technology and Science, Chennai – 603103, Tamil Nadu, IN
2 School of Computer Sciences, Hindustan Institute of Technology & Science, Chennai - 603103, Tamil Nadu, IN
1 Department of Computer Science and Engineering, Hindustan Institute of Technology and Science, Chennai – 603103, Tamil Nadu, IN
2 School of Computer Sciences, Hindustan Institute of Technology & Science, Chennai - 603103, Tamil Nadu, IN
Source
Indian Journal of Science and Technology, Vol 10, No 42 (2017), Pagination:Abstract
Objectives: In IOT environment, an electric grid has security and privacy issues. Security technique in a 24*7-enterprise environment with evaluation of using real time based encryption for security, privacy to achieve IoT security. Methods/Statistical Analysis: Cryptography technique such as Homomorphism Encryption secures the data preventing from unauthorized software or firmware to access data in a known format. Differential Privacy is used to maintain privacy to protect personal information. Findings: Securing data readings in real-time is interesting and extremely challenging as all the data and privacy information to be prevented from hacking. Application/Improvements: The security measures described can be applied to smart grid, smart meter IOT environment, Machine-to-Machine Environment.Keywords
Gortis Enhanced Homomorphic Encryption, Industrial Control System, Internet of Things, Machine-MachineFull Text